Tirzepatide

Active substance Tirzepatide

Tirzepatide (hereinafter referred to as tirzepatide) is a medicinal product for weight loss. It helps to increase sugar metabolism in the body. The drug is intended for patients diagnosed with obesity or type 2 diabetes mellitus. A clinical study, in which the elaborate formula was tested, resulted in an average weight loss of 26.6%. You can buy tirzepatide in our online shop.

The active substance of the new drug is Tirzepatide (Tirzepatide). Its task is to activate the body's receptors for natural incretins (hormones like GLP-1 and GIP). As each receptor enters the activation stage, the body begins to release insulin. The receptors are located in each of the areas of the human brain responsible for appetite regulation.

After trying this product, it turned out that thanks to this substance it is easier to modulate fat metabolism. Nevertheless, until recently, the mechanism of influence on metabolism remained unclear. But after another study it was found that signalling pathways in islet cells through the GIP-receptor contributes to the production of insulin during therapy.

Pharmacological action 

Pharmacological action is to increase the body's sensitivity to insulin. In addition, taking the drug allows to increase insulin production, in parallel reducing blood sugar levels.

The effectiveness of pharmacological action is confirmed by the reduction of glucose content in the body after eating and on an empty stomach. Deciding to buy tirzepatide in England through our online shop, the buyer should understand that the drug, activating the cell receptor, has anorexigenic effect (reduces the urge to eat) and reduces body weight.

Brands of the substance Tirzepatide

Currently, the only brand offering tirzepatide in England is Mounjaro (Mounjaro). In the United States, another name of the drug is Zepbound.

Indications and effects 

The only indication of the drug is the treatment of type 2 diabetes mellitus. It is intended for adult patients.

Tirsepatide is used as an adjunct to the diet. It is also used as a weight loss enhancer in combination with exercise.

Contraindications to the use of Tirzepatide

Despite its advantages, before you buy tirzepatide in England, it is necessary to familiarise yourself with contraindications as well. And they are also present here. It is forbidden to use the drug in such internal diseases and conditions:

• individual intolerance of the body to active substances that are included in the drug;
• occurrence of side effects;
• family or personal history of MTCT;
• endocrine multiple neoplasia type 2.

If there are suspicions of individual intolerance to the drug, it is necessary to immediately stop taking it and consult with the attending physician. On the basis of the results obtained, a decision is made on the correction of dosages or complete closure of the course.

Side effects and contraindications to use

Some users of the drug may experience side effects. During clinical studies, specialists found out that some patients may experience such problems as:

• vomiting;
• nausea;
• constipation;
• diarrhoea.

It is important to note that these side effects are able to increase if the patient starts taking increased doses. Therefore, before starting a course of treatment, it is necessary to carefully read the instructions of tirzepatide. If the side effects become more severe, you need to temporarily stop taking the drug and consult with your doctor.

Course of Tirzepatide

The development of an individual course of intake is handled by the attending physician on the basis of a complete examination of the person. To get rid of 20% of excess weight, the average course lasts about 72 weeks.

The maximum dosage should not exceed 15 mg of the drug per injection. They should be given once a week. When using the maximum dose, the average fat loss rate is 22.5 per cent. When going through an individual course of taking the drug, it is necessary to be sure to observe all doses. If the patient has renal failure, regardless of its degree, no dose adjustment is required. A similar rule applies to renal failure.

The drug is administered once a week. In the first month, the initial dose is 2.5 mg, and then it is increased to 5 mg. If additional glycaemic control is required, the current dose should be increased by 2.5 milligrams at least one month from the current dose. It should be understood that the initial dose is used in therapy and preparation for a full course. Therefore, it will not be effective for glycaemic control.

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If you have additional questions, you can always consult our experts. We will gladly provide detailed answers by phone or online. The price of tirzepatide in England, indicated on the website, is current at the time of viewing the catalogue.